Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities

INTRODUCTION: Zellweger spectrum disorder (PBD-ZSD) is a disease continuum caused by mutations in a subset of PEX genes required for normal peroxisome assembly and function. They highlight the importance of peroxisomes in the development and functions of the central nervous system, liver, and other...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Wang, Xiao-Ming, Yik, Wing Yan, Zhang, Peilin, Lu, Wange, Huang, Ning, Kim, Bo Ram, Shibata, Darryl, Zitting, Madison, Chow, Robert H., Moser, Ann B., Steinberg, Steven J., Hacia, Joseph G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553005/
https://ncbi.nlm.nih.gov/pubmed/26319495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0149-3
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi