Encapsulated Brucella ovis Lacking a Putative ATP-Binding Cassette Transporter (ΔabcBA) Protects against Wild Type Brucella ovis in Rams

This study aimed to evaluate protection induced by the vaccine candidate B. ovis ΔabcBA against experimental challenge with wild type B. ovis in rams. Rams were subcutaneously immunized with B. ovis ΔabcBA encapsulated with sterile alginate or with the non encapsulated vaccine strain. Serum, urine,...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Silva, Ana Patrícia C., Macêdo, Auricélio A., Costa, Luciana F., Rocha, Cláudia E., Garcia, Luize N. N., Farias, Jade R. D., Gomes, Priscilla P. R., Teixeira, Gustavo C., Fonseca, Kessler W. J., Maia, Andréa R. F., Neves, Gabriela G., Romão, Everton L., Silva, Teane M. A., Mol, Juliana P. S., Oliveira, Renata M., Araújo, Márcio S. S., Nascimento, Ernane F., Martins-Filho, Olindo A., Brandão, Humberto M., Paixão, Tatiane A., Santos, Renato L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552948/
https://ncbi.nlm.nih.gov/pubmed/26317399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136865
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