Encapsulated Brucella ovis Lacking a Putative ATP-Binding Cassette Transporter (ΔabcBA) Protects against Wild Type Brucella ovis in Rams

This study aimed to evaluate protection induced by the vaccine candidate B. ovis ΔabcBA against experimental challenge with wild type B. ovis in rams. Rams were subcutaneously immunized with B. ovis ΔabcBA encapsulated with sterile alginate or with the non encapsulated vaccine strain. Serum, urine,...

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Veröffentlicht in:PLoS One
Hauptverfasser: Silva, Ana Patrícia C., Macêdo, Auricélio A., Costa, Luciana F., Rocha, Cláudia E., Garcia, Luize N. N., Farias, Jade R. D., Gomes, Priscilla P. R., Teixeira, Gustavo C., Fonseca, Kessler W. J., Maia, Andréa R. F., Neves, Gabriela G., Romão, Everton L., Silva, Teane M. A., Mol, Juliana P. S., Oliveira, Renata M., Araújo, Márcio S. S., Nascimento, Ernane F., Martins-Filho, Olindo A., Brandão, Humberto M., Paixão, Tatiane A., Santos, Renato L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552948/
https://ncbi.nlm.nih.gov/pubmed/26317399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136865
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