Protection Provided by an Encapsulated Live Attenuated ΔabcBA Strain of Brucella ovis against Experimental Challenge in a Murine Model

This study aimed to evaluate the Brucella ovis ΔabcBA strain as a vaccine candidate in the murine model. BALB/c mice were subcutaneously or intraperitoneally immunized with a single dose or three doses of the B. ovis ΔabcBA strain and then were challenged with wild-type B. ovis. Single or multiple i...

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Detalhes bibliográficos
Publicado no:Clin Vaccine Immunol
Main Authors: Silva, Ana Patrícia C., Macêdo, Auricélio A., Silva, Teane M. A., Ximenes, Luana C. A., Brandão, Humberto M., Paixão, Tatiane A., Santos, Renato L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4478529/
https://ncbi.nlm.nih.gov/pubmed/25947146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00191-15
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