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Molecular Dissection of the Human Ubiquitin C Promoter Reveals Heat Shock Element Architectures with Activating and Repressive Functions

The promoter of the polyubiquitin C gene (UBC) contains putative heat shock elements (HSEs) which are thought to mediate UBC induction upon stress. However, the mapping and the functional characterization of the cis-acting determinants for its up-regulation have not yet been addressed. In this study...

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Publicado en:PLoS One
Autores principales: Crinelli, Rita, Bianchi, Marzia, Radici, Lucia, Carloni, Elisa, Giacomini, Elisa, Magnani, Mauro
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552642/
https://ncbi.nlm.nih.gov/pubmed/26317694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136882
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