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Quantitative Connection Between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryo-EM and smFRET Investigations of the Ribosome

At equilibrium, thermodynamic and kinetic information can be extracted from biomolecular energy landscapes by many techniques. However, while static, ensemble techniques yield thermodynamic data, often only dynamic, single-molecule techniques can yield the kinetic data that describes transition-stat...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Thompson, Colin D. Kinz, Sharma, Ajeet K., Frank, Joachim, Gonzalez, Ruben L., Chowdhury, Debashish
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552622/
https://ncbi.nlm.nih.gov/pubmed/25785884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp5128805
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