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Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice
To clarify the effect of secretory IgA (sIgA) deficiency on gut homeostasis, we examined intraepithelial lymphocytes (IELs) in the small intestine (SI) of polymeric immunoglobulin receptor-deficient (pIgR(−/−)) mice. The pIgR(−/−) mice exhibited the accumulation of CD8αβ(+) T-cell receptor (TCR)-αβ(...
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| Pubblicato in: | Immunology |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley & Sons, Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4552501/ https://ncbi.nlm.nih.gov/pubmed/25967857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12480 |
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