Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice

To clarify the effect of secretory IgA (sIgA) deficiency on gut homeostasis, we examined intraepithelial lymphocytes (IELs) in the small intestine (SI) of polymeric immunoglobulin receptor-deficient (pIgR(−/−)) mice. The pIgR(−/−) mice exhibited the accumulation of CD8αβ(+) T-cell receptor (TCR)-αβ(...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Kato-Nagaoka, Noriko, Shimada, Shin-Ichiro, Yamakawa, Yoko, Tsujibe, Satoshi, Naito, Tomoaki, Setoyama, Hiromi, Watanabe, Yohei, Shida, Kan, Matsumoto, Satoshi, Nanno, Masanobu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552501/
https://ncbi.nlm.nih.gov/pubmed/25967857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12480
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