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Autologous cellular vaccine overcomes cancer immunoediting in a mouse model of myeloma
In the Sp6 mouse plasmacytoma model, a whole-cell vaccination with Sp6 cells expressing de novo B7-1 (Sp6/B7) induced anatomically localized and cytotoxic T cell (CTL) -mediated protection against wild-type (WT) Sp6. Both WT Sp6 and Sp6/B7 showed down-regulated expression of MHC H-2 L(d). Increase o...
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出版年: | Immunology |
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主要な著者: | , , , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
John Wiley & Sons, Ltd
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4552499/ https://ncbi.nlm.nih.gov/pubmed/25959091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12477 |
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