Autologous cellular vaccine overcomes cancer immunoediting in a mouse model of myeloma

In the Sp6 mouse plasmacytoma model, a whole-cell vaccination with Sp6 cells expressing de novo B7-1 (Sp6/B7) induced anatomically localized and cytotoxic T cell (CTL) -mediated protection against wild-type (WT) Sp6. Both WT Sp6 and Sp6/B7 showed down-regulated expression of MHC H-2 L(d). Increase o...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Mazzocco, Marta, Martini, Matteo, Rosato, Antonio, Stefani, Elisabetta, Matucci, Andrea, Dalla Santa, Silvia, De Sanctis, Francesco, Ugel, Stefano, Sandri, Sara, Ferrarini, Giovanna, Cestari, Tiziana, Ferrari, Sergio, Zanovello, Paola, Bronte, Vincenzo, Sartoris, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552499/
https://ncbi.nlm.nih.gov/pubmed/25959091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12477
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