PARD3 induces TAZ activation and cell growth by promoting LATS1 and PP1 interaction

The Hippo pathway plays a major role in organ size control, and its dysregulation contributes to tumorigenesis. The major downstream effectors of the Hippo pathway are the YAP/TAZ transcription co-activators, which are phosphorylated and inhibited by the Hippo pathway kinase LATS1/2. Here, we report...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:EMBO Rep
Huvudupphovsmän: Lv, Xian-Bo, Liu, Chen-Ying, Wang, Zhen, Sun, Yi-Ping, Xiong, Yue, Lei, Qun-Ying, Guan, Kun-Liang
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Ltd 2015
Ämnen:
Scientific Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552490/
https://ncbi.nlm.nih.gov/pubmed/26116754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439951
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk