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Type I Interferons Function as Autocrine and Paracrine Factors to Induce Autotaxin in Response to TLR Activation

Lysophosphatidic acid (LPA) is an important phospholipid mediator in inflammation and immunity. However, the mechanism of LPA regulation during inflammatory response is largely unknown. Autotaxin (ATX) is the key enzyme to produce extracellular LPA from lysophosphatidylcholine (LPC). In this study,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Song, Jianwen, Guan, Ming, Zhao, Zhenwen, Zhang, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552386/
https://ncbi.nlm.nih.gov/pubmed/26313906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136629
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