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Intermediate Tyrosyl Radical and Amyloid Structure in Peroxide-Activated Cytoglobin

We characterized the peroxidase mechanism of recombinant rat brain cytoglobin (Cygb) challenged by hydrogen peroxide, tert-butylhydroperoxide and by cumene hydroperoxide. The peroxidase mechanism of Cygb is similar to that of myoglobin. Cygb challenged by hydrogen peroxide is converted to a Fe(4+) o...

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Publicat a:PLoS One
Autors principals: Ferreira, Juliana C., Marcondes, Marcelo F., Icimoto, Marcelo Y., Cardoso, Thyago H. S., Tofanello, Aryane, Pessoto, Felipe S., Miranda, Erica G. A., Prieto, Tatiana, Nascimento, Otaciro R., Oliveira, Vitor, Nantes, Iseli L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552303/
https://ncbi.nlm.nih.gov/pubmed/26312997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136554
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