Tumor-targeting, pH-sensitive nanoparticles for docetaxel delivery to drug-resistant cancer cells

The attachment of polyethylene glycol (PEG) increases the circulation time of drug-containing nanoparticles; however, this also negatively affects cellular uptake. To overcome this problem, unique lipid polymer hybrid (LPH) nanoparticles were developed with a pH-responsive PEG layer that detached pr...

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Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Tran, Tuan Hiep, Ramasamy, Thiruganesh, Choi, Ju Yeon, Nguyen, Hanh Thuy, Pham, Thanh Tung, Jeong, Jee-Heon, Ku, Sae Kwang, Choi, Han-Gon, Yong, Chul Soon, Kim, Jong Oh
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552257/
https://ncbi.nlm.nih.gov/pubmed/26346426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S89584
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