Erythropoietin Attenuates Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension through Interplay between Endothelial Progenitor Cells and Heme Oxygenase

BACKGROUND: Pulmonary arterial hypertension (PAH) is a pulmonary vascular disease with a high mortality, characterized by typical angio-proliferative lesions. Erythropoietin (EPO) attenuates pulmonary vascular remodeling in PAH. We postulated that EPO acts through mobilization of endothelial progeni...

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Dettagli Bibliografici
Pubblicato in:Front Pediatr
Autori principali: van Loon, Rosa Laura E., Bartelds, Beatrijs, Wagener, Frank A. D. T. G., Affara, Nada, Mohaupt, Saffloer, Wijnberg, Hans, Pennings, Sebastiaan W. C., Takens, Janny, Berger, Rolf M. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Pediatrics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551834/
https://ncbi.nlm.nih.gov/pubmed/26380246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2015.00071
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