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Amino acid activation of mTORC1 by a PB1-domain-driven kinase complex cascade
The mTORC1 complex is central to the cellular response to changes in nutrient availability. The signaling adapter p62 contributes to mTORC1 activation in response to amino acids, and interacts with TRAF6, which is required for the translocation of mTORC1 to the lysosome and the subsequent K63-polyub...
Tallennettuna:
| Julkaisussa: | Cell Rep |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551582/ https://ncbi.nlm.nih.gov/pubmed/26279575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.045 |
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