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p62 is a key regulator of nutrient sensing in the mTORC1 pathway

The signaling adapter p62 is a critical mediator of important cellular functions owing to its ability to establish interactions with various signaling intermediaries. Here we identify raptor as an interacting partner of p62. Thus, p62 is an integral part of the mTORC1 complex, and is necessary to me...

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Détails bibliographiques
Auteurs principaux: Duran, Angeles, Amanchy, Ramars, Linares, Juan F., Joshi, Jayashree, Abu-Baker, Shadi, Porollo, Alexey, Hansen, Malene, Moscat, Jorge, Diaz-Meco, Maria T.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190169/
https://ncbi.nlm.nih.gov/pubmed/21981924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.038
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