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A cell permeable ATP analog for kinase-catalyzed biotinylation

ATP analogs have been powerful tools in the study of kinase-catalyzed phosphorylation. However, the cell impermeability of ATP analogs has largely limited their use to in vitro lysate-based experiments. Here we report the first cell permeable ATP analog, ATP-polyamine-biotin (APB). APB promoted biot...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Fouda, Ahmed E., Pflum, Mary Kay H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551444/
https://ncbi.nlm.nih.gov/pubmed/26119262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201503041
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