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Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis

The complement anaphylatoxin C5a is a critical mediator of allergic contact dermatitis, bridging essential aspects of innate and adaptive immunity. This anaphylatoxin functions by interacting with two 7-transmembrane segment (TMS) receptors, the C5aR and C5L2. The C5aR is a classical G protein coupl...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wang, Ruobing, Lu, Bao, Gerard, Craig, Gerard, Norma P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551435/
https://ncbi.nlm.nih.gov/pubmed/24043888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301626
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