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Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis
The complement anaphylatoxin C5a is a critical mediator of allergic contact dermatitis, bridging essential aspects of innate and adaptive immunity. This anaphylatoxin functions by interacting with two 7-transmembrane segment (TMS) receptors, the C5aR and C5L2. The C5aR is a classical G protein coupl...
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| Published in: | J Immunol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551435/ https://ncbi.nlm.nih.gov/pubmed/24043888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301626 |
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