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Lenalidomide augments actin remodeling and lowers NK-cell activation thresholds
As multiple myeloma (MM) progresses, natural killer (NK)-cell responses decline against malignant plasma cells. The immunomodulatory drug lenalidomide is widely used for treatment of MM but its influence on NK-cell biology is unclear. Here, we report that lenalidomide lowers the threshold for NK-cel...
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| Publicado no: | Blood |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551357/ https://ncbi.nlm.nih.gov/pubmed/26002964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-625004 |
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