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Generation of induced pluripotent stem cells from renal tubular cells of a patient with Alport syndrome
Alport syndrome (AS) is a hereditary disease that leads to kidney failure and is caused by mutations in the COL4A3, COL4A4, and COL4A5 genes that lead to the absence of collagen α3α4α5 (IV) networks in the mature kidney glomerular basement membrane. Approximately 80% of AS is X-linked because of mut...
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| Publicado no: | Int J Nephrol Renovasc Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551301/ https://ncbi.nlm.nih.gov/pubmed/26345127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJNRD.S85733 |
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