Activation of PPARδ signaling improves skeletal muscle oxidative metabolism and endurance function in an animal model of ischemic left ventricular dysfunction

Exercise intolerance in heart failure has been linked to impaired skeletal muscle oxidative capacity. Oxidative metabolism and exercise capacity are regulated by PPARδ signaling. We hypothesized that PPARδ stimulation reverts skeletal muscle oxidative dysfunction. Myocardial infarction (MI) was indu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Zizola, Cynthia, Kennel, Peter J., Akashi, Hirokazu, Ji, Ruiping, Castillero, Estibaliz, George, Isaac, Homma, Shunichi, Schulze, P. Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Energetics and Metabolism
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551122/
https://ncbi.nlm.nih.gov/pubmed/25713305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00679.2014
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