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Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers

BACKGROUND & AIMS: The ratio of liver size to body weight (hepatostat) is tightly controlled, but little is known about how the physiologic functions of the liver help determine its size. Livers of mice repopulated with human hepatocytes (humanized livers) grow to larger than normal; the human h...

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Foilsithe in:Gastroenterology
Main Authors: Naugler, Willscott E., Tarlow, Branden D., Fedorov, Lev M., Taylor, Matthew, Pelz, Carl, Li, Bin, Darnell, Jennifer, Grompe, Markus
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550566/
https://ncbi.nlm.nih.gov/pubmed/26028580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.05.043
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