Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers

BACKGROUND & AIMS: The ratio of liver size to body weight (hepatostat) is tightly controlled, but little is known about how the physiologic functions of the liver help determine its size. Livers of mice repopulated with human hepatocytes (humanized livers) grow to larger than normal; the human h...

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Publié dans:Gastroenterology
Auteurs principaux: Naugler, Willscott E., Tarlow, Branden D., Fedorov, Lev M., Taylor, Matthew, Pelz, Carl, Li, Bin, Darnell, Jennifer, Grompe, Markus
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550566/
https://ncbi.nlm.nih.gov/pubmed/26028580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.05.043
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