Fibrin-genipin annulus fibrosus sealant as a delivery system for anti-TNFα drug

BACKGROUND CONTEXT: Intervertebral discs (IVD) are attractive targets for local drug delivery because they are avascular structures with limited transport. Painful IVDs are in a chronic inflammatory state. While anti-inflammatories show poor performance in clinical trials their efficacy treating IVD...

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Detalhes bibliográficos
Publicado no:Spine J
Main Authors: Likhitpanichkul, Morakot, Kim, Yesul, Torre, Olivia M, See, Eugene, Kazezian, Zepur, Pandit, Abhay, Hecht, Andrew C, Iatridis, James C
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550557/
https://ncbi.nlm.nih.gov/pubmed/25912501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.spinee.2015.04.026
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