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Oligonucleotide aptamer-drug conjugates for targeted therapy of acute myeloid leukemia
Oligonucleotide aptamers can specifically bind biomarkers on cancer cells and can be readily chemically modified with different functional molecules for personalized medicine. To target acute myeloid leukemia (AML) cells, we developed a single-strand DNA aptamer specific for the biomarker CD117, whi...
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| Publicado no: | Biomaterials |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550516/ https://ncbi.nlm.nih.gov/pubmed/26204224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.07.025 |
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