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A Cancer Cell-Activatable Aptamer-Reporter System for One-Step Assay of Circulating Tumor Cells

The current antibody-mediated numeration assays of circulating tumor cells (CTCs) require multiple steps and are time-consuming. To overcome these technical limitations, a cancer cell-activatable aptamer-reporter was formulated by conjugating a biomarker-specific aptamer sequence with paired fluoroc...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Zeng, Zihua, Tung, Ching-Hsuan, Zu, Youli
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221596/
https://ncbi.nlm.nih.gov/pubmed/25118170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.36
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