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Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact

Deciphering the multitude of epigenomic and genomic factors that influence the mutation rate is an area of great interest in modern biology. Recently, chromatin has been shown to play a part in this process. To elucidate this relationship further, we integrated our own ultra-deep sequenced human nuc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yazdi, Puya G., Pedersen, Brian A., Taylor, Jared F., Khattab, Omar S., Chen, Yu-Han, Chen, Yumay, Jacobsen, Steven E., Wang, Ping H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550472/
https://ncbi.nlm.nih.gov/pubmed/26308346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136574
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