Statins, HMG-CoA Reductase Inhibitors, Improve Neovascularization by Increasing the Expression Density of CXCR4 in Endothelial Progenitor Cells

Statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, are used to reduce cholesterol biosynthesis in the liver. Accordingly, statins regulate nitric oxide (NO) and glutamate metabolism, inflammation, angiogenesis, immunity and endothelial progenitor cells (EPCs) functions...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Chiang, Kuang-Hsing, Cheng, Wan-Li, Shih, Chun-Ming, Lin, Yi-Wen, Tsao, Nai-Wen, Kao, Yung-Ta, Lin, Chih-Ting, Wu, Shinn-Chih, Huang, Chun-Yao, Lin, Feng-Yen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550447/
https://ncbi.nlm.nih.gov/pubmed/26309120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136405
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