Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation

Accumulating evidence supports the idea that secondary metabolites obtained from medicinal plants (phytometabolites) may be important contributors in the development of new chemotherapeutic agents to reduce the occurrence or recurrence of cancer. Our study focused on Dehydroleucodine (DhL), a sesqui...

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Опубликовано в: :PLoS One
Главные авторы: Bailon-Moscoso, Natalia, González-Arévalo, Gabriela, Velásquez-Rojas, Gabriela, Malagon, Omar, Vidari, Giovanni, Zentella-Dehesa, Alejandro, Ratovitski, Edward A., Ostrosky-Wegman, Patricia
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550445/
https://ncbi.nlm.nih.gov/pubmed/26309132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136527
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