Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 Regulation

Accumulating evidence supports the idea that secondary metabolites obtained from medicinal plants (phytometabolites) may be important contributors in the development of new chemotherapeutic agents to reduce the occurrence or recurrence of cancer. Our study focused on Dehydroleucodine (DhL), a sesqui...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bailon-Moscoso, Natalia, González-Arévalo, Gabriela, Velásquez-Rojas, Gabriela, Malagon, Omar, Vidari, Giovanni, Zentella-Dehesa, Alejandro, Ratovitski, Edward A., Ostrosky-Wegman, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550445/
https://ncbi.nlm.nih.gov/pubmed/26309132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136527
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