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Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding
RAS proteins are signal transduction gatekeepers that mediate cell growth, survival, and differentiation through interactions with multiple effector proteins. The RAS effector RAS- and RAB-interacting protein 1 (RIN1) activates its own downstream effectors, the small GTPase RAB5 and the tyrosine kin...
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| 發表在: | FASEB J |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Federation of American Societies for Experimental Biology
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550377/ https://ncbi.nlm.nih.gov/pubmed/25999467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-271510 |
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