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A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells

Temozolomide (TMZ) is an oral alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma (GBM). Despite that high TMZ potential, progression of disease and recurrence are still observed. Therefore a better understanding of the mechanism of action of this drug is neces...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Barciszewska, Anna-Maria, Gurda, Dorota, Głodowicz, Paweł, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550362/
https://ncbi.nlm.nih.gov/pubmed/26309255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136669
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