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A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells

Temozolomide (TMZ) is an oral alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma (GBM). Despite that high TMZ potential, progression of disease and recurrence are still observed. Therefore a better understanding of the mechanism of action of this drug is neces...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Barciszewska, Anna-Maria, Gurda, Dorota, Głodowicz, Paweł, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550362/
https://ncbi.nlm.nih.gov/pubmed/26309255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136669
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