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LytB1 and LytB2 of Mycobacterium tuberculosis Are Not Genetically Redundant

Mycobacterium tuberculosis synthesises isoprenoid precursors via the MEP/DOXP pathway and at least five enzymes in the pathway (Dxs1, Dxr/IspC, IspD, IspF, and GcpE/IspG) are required for growth in vitro. We investigated the role of LytB (IspH) in M. tuberculosis; M. tuberculosis is unusual in that...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brown, Amanda Claire, Kokoczka, Rachel, Parish, Tanya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550268/
https://ncbi.nlm.nih.gov/pubmed/26309039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135638
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