Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy

X-linked adrenoleukodystrophy is a neurometabolic disorder caused by inactivation of the peroxisomal ABCD1 transporter of very long-chain fatty acids. In mice, ABCD1 loss causes late onset axonal degeneration in the spinal cord in association with locomotor disability resembling the most common phen...

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Veröffentlicht in:Brain
Hauptverfasser: Morató, Laia, Galino, Jorge, Ruiz, Montserrat, Calingasan, Noel Ylagan, Starkov, Anatoly A., Dumont, Magali, Naudí, Alba, Martínez, Juan José, Aubourg, Patrick, Portero-Otín, Manuel, Pamplona, Reinald, Galea, Elena, Beal, M. Flint, Ferrer, Isidre, Fourcade, Stéphane, Pujol, Aurora
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550111/
https://ncbi.nlm.nih.gov/pubmed/23794606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt143
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