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Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy
X-linked adrenoleukodystrophy is a neurometabolic disorder caused by inactivation of the peroxisomal ABCD1 transporter of very long-chain fatty acids. In mice, ABCD1 loss causes late onset axonal degeneration in the spinal cord in association with locomotor disability resembling the most common phen...
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Publicat a: | Brain |
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Autors principals: | , , , , , , , , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Oxford University Press
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550111/ https://ncbi.nlm.nih.gov/pubmed/23794606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt143 |
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