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Over-expressing Akt in T cells to resist tumor immunosuppression and increase anti-tumor activity
BACKGROUND: Tumor employs various means to escape immunosurveillance and inhibit immune attack, and strategies have been developed to counteract the inhibitory signals. However, due to the complex suppressive mechanisms in the tumor microenvironment, blocking one or a few inhibitory signals has only...
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| Veröffentlicht in: | BMC Cancer |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550078/ https://ncbi.nlm.nih.gov/pubmed/26310246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1611-4 |
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