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Over-expressing Akt in T cells to resist tumor immunosuppression and increase anti-tumor activity

BACKGROUND: Tumor employs various means to escape immunosurveillance and inhibit immune attack, and strategies have been developed to counteract the inhibitory signals. However, due to the complex suppressive mechanisms in the tumor microenvironment, blocking one or a few inhibitory signals has only...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Wu, Yanhong, Deng, Zhenling, Tang, Yishu, Zhang, Shuren, Zhang, Yu-Qian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550078/
https://ncbi.nlm.nih.gov/pubmed/26310246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1611-4
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