A physical association between the human mutY homolog (hMYH) and DNA topoisomerase II-binding protein 1 (hTopBP1) regulates Chk1-induced cell cycle arrest in HEK293 cells

BACKGROUND: Human DNA topoisomerase II-binding protein 1 (hTopBP1) plays an important role in DNA replication and the DNA damage checkpoint pathway. The human mutY homolog (hMYH) is a base excision repair DNA glycosylase that excises adenines or 2-hydroxyadenines that are mispaired with guanine or 7...

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Vydáno v:Cell Biosci
Hlavní autoři: Han, Se Hee, Hahm, Soo-Hyun, Tran, An Hue Vy, Chung, Ji Hyung, Hong, Myoung-Ki, Paik, Hyun-Dong, Kim, Key-Sun, Han, Ye Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550056/
https://ncbi.nlm.nih.gov/pubmed/26312135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0042-x
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