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Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis

The MutY homolog (MYH) can excise adenines misincorporated opposite to guanines or 7, 8-dihydro-8-oxo-guanines (8-oxoG) during DNA replication; thereby preventing G:C to T:A transversions. Germline mutations in the human MYH gene are associated with recessive inheritance of colorectal adenomatous po...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bai, Haibo, Grist, Scott, Gardner, Justin, Suthers, Graeme, Wilson, Teresa M., Lu, A-Lien
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907362/
https://ncbi.nlm.nih.gov/pubmed/17081686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2006.09.016
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