Caspase-7: a critical mediator of optic nerve injury-induced retinal ganglion cell death

BACKGROUND: Axonal injury of the optic nerve (ON) is involved in various ocular diseases, such as glaucoma and traumatic optic neuropathy, which leads to apoptotic death of retinal ganglion cells (RGCs) and loss of vision. Caspases have been implicated in RGC pathogenesis. However, the role of caspa...

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Udgivet i:Mol Neurodegener
Main Authors: Choudhury, Shreyasi, Liu, Yang, Clark, Abbot F., Pang, Iok-Hou
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550044/
https://ncbi.nlm.nih.gov/pubmed/26306916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0039-2
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