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Mapping complex disease traits with global gene expression

Variation in gene expression is an important mechanism underlying susceptibility to complex disease. The simultaneous genome-wide assay of gene expression and genetic variation allows the mapping of the genetic factors that underpin individual differences in quantitative levels of expression (expres...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Rev Genet
Main Authors: Cookson, William, Liang, Liming, Abecasis, Gonçalo, Moffatt, Miriam, Lathrop, Mark
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550035/
https://ncbi.nlm.nih.gov/pubmed/19223927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2537
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