Characterization of Gastric Mucosa Biopsies Reveals Alterations in Huntington's Disease

Weight loss is an important complication of Huntington’s disease (HD), however the mechanism for weight loss in HD is not entirely understood. Mutant huntingtin is expressed in the gastrointestinal (GI) tract and, in HD mice, mutant huntingtin inclusions are found within the enteric nervous system a...

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Detalhes bibliográficos
Publicado no:PLoS Curr
Main Authors: McCourt, Andrew C, O'Donovan, Kirsty L, Ekblad, Eva, Sand, Elin, Craufurd, David, Rosser, Anne, Sanders, David, Stoy, Nicholas, Rickards, Hugh, Wierup, Nils, Bates, Gillian P., Björkqvist, Maria, Quarrell, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549855/
https://ncbi.nlm.nih.gov/pubmed/26581667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.hd.858b4cc7f235df068387e9c20c436a79
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