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Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington’s disease
Accumulating evidence suggests altered energy metabolism as a key feature in Huntington’s disease (HD) pathology. Hyper-catabolism, including weight loss and muscle atrophy, is seen in HD patients and HD mouse models. Metabolic hormones are key players, not only in energy metabolism, but also in neu...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654969/ https://ncbi.nlm.nih.gov/pubmed/29066728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13713-5 |
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