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Molecular Cloning and Functional Analysis of Gene Clusters for the Biosynthesis of Indole-Diterpenes in Penicillium crustosum and P. janthinellum

The penitremane and janthitremane families of indole-diterpenes are abundant natural products synthesized by Penicillium crustosum and P. janthinellum. Using a combination of PCR, cosmid library screening, and Illumina sequencing we have identified gene clusters encoding enzymes for the synthesis of...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Principais autores: Nicholson, Matthew J., Eaton, Carla J., Stärkel, Cornelia, Tapper, Brian A., Cox, Murray P., Scott, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549719/
https://ncbi.nlm.nih.gov/pubmed/26213965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7082701
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