Functional three-domain single-chain T-cell receptors.

T-cell receptors (TCRs) are membrane anchored heterodimers structurally related to antibody molecules. Single-chain antibodies can be engineered by linking the two variable domains, which fold properly by themselves. However, proper assembly of the variable domains of a human TCR (V alpha and V beta...

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Bibliografiske detaljer
Main Authors: Chung, S, Wucherpfennig, K W, Friedman, S M, Hafler, D A, Strominger, J L
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45497/
https://ncbi.nlm.nih.gov/pubmed/7809095
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