Functional three-domain single-chain T-cell receptors.
T-cell receptors (TCRs) are membrane anchored heterodimers structurally related to antibody molecules. Single-chain antibodies can be engineered by linking the two variable domains, which fold properly by themselves. However, proper assembly of the variable domains of a human TCR (V alpha and V beta...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1994
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45497/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7809095/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12654 |
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