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Preclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and Validation

Over the past 35 years, cure rates for pediatric cancers have increased dramatically. However, it is clear that further dose intensification using cytotoxic agents or radiation therapy is not possible without enhancing morbidity and long-term effects. Consequently, novel, less genotoxic, agents are...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Geier, Brian, Kurmashev, Dias, Kurmasheva, Raushan T., Houghton, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549564/
https://ncbi.nlm.nih.gov/pubmed/26380223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00193
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