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Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
Mutations in the Pax6 gene cause ocular defects in both vertebrate and invertebrate animal species, and the disease aniridia in humans. Despite extensive experimentation on this gene in multiple species, including humans, we still do not understand the earliest effects on development mediated by thi...
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| 出版年: | Dev Biol |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549229/ https://ncbi.nlm.nih.gov/pubmed/25724657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.02.012 |
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